HEPARIN CONTAMINATION OF SPECIMENS COLLECTED FROM ARTERIAL CANNULAE
نویسندگان
چکیده
منابع مشابه
Lessons learned from the contamination of heparin.
Heparin is unique as one of the oldest drugs currently still in widespread clinical use as an anticoagulant, a natural product, one of the first biopolymeric drugs, and one of the few carbohydrate drugs. Recently, certain batches of heparin have been associated with anaphylactoid-type reactions, some leading to hypotension and death. These reactions were traced to contamination with a semi-synt...
متن کاملPhosphate contamination of commercial heparin.
Heparin is widely used as an anticoagulant in biochemical laboratories. Hawk, Oser, and Summerson (1947) state that heparin is an excellent anticoagulant, as it does not alter the distribution of diffusible substances between cells and plasma. Jorpes (1946) states that heparin neither influences the volume of the blood corpuscles nor interferes with the chemical analysis. In the course of routi...
متن کاملContamination of coagulation tests with heparin from blood gas samples.
We investigated the possibility that samples of blood could be contaminated by heparinized blood gas syringes, giving spurious results in coagulation tests. We collected coagulation test samples before (n=5) and after (n=13) blood gas sampling from a venous cannula in a volunteer. The results of activated partial thromboplastin time (APTT) tests were compared between control samples and samples...
متن کاملSecondary septicaemia from intravenous cannulae.
Within a period of only seven months three patients in one hospital under treatment with antibiotics by intravenous infusion developed secondary bloodstream infection originating from the site of insertion of the cannula. Two of these infections were fatal. Precautions suggested include strict asepsis, the skin being sterilized with iodine in spirit solution; antibiotic spray; and changing the ...
متن کاملMinimum volume of discard for valid blood sampling from indwelling arterial cannulae.
The volume of discard for valid blood sampling from indwelling femoral (leader cath) and radial (Venflon) arterial cannulae (with internal volume of cannula plus connecting tubing of approximately 2 ml) was investigated by analysing sequential 2-ml aliquots of 10-ml samples. The aliquots were analysed for pH, carbon dioxide tension, oxygen tension, standard bicarbonate, haemoglobin concentratio...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1993
ISSN: 0007-0912
DOI: 10.1093/bja/71.2.322-a